In This Section
Practice Guidelines
**PLEASE NOTE: As of February 2014, the Society of Nuclear Medicine and Molecular Imaging (SNMMI) Guidelines will now be referred to as Procedure Standards. This change was initiated in an effort to better reflect the terminology being used by external organizations. Any previous Practice Guideline or Procedure Guideline that describes how to perform a procedure is now considered an SNMMI Procedure Standard.**
The practice guidelines help to identify those elements of the procedure that are most important in obtaining a high-quality examination, while simultaneously controlling costs. Use of standardized procedures will increase the applicability of clinical research among multiple institutions, in turn, increasing the value of research studies, particularly in the field of technology assessment. In the interest of creating strong, comprehensive documents, some guidelines were formally adopted by SNMMI in collaboration with other professional organizations.
Comments or Questions?
The Committee on SNMMI Guidelines is continually developing new guidelines and reviewing and updating existing guidelines. If you have specific comments or questions on the content of any of the guidelines, or if you have suggestions for new guidelines that you feel should be written, please contact the Committee at hpra@snmmi.org. All comments will be considered in the guideline development process.
Cardiovascular System |
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Date Approved |
Document title |
| November 15, 2012 | ASNC-SCCT-SNMMI Guideline for Cardiac SPECT/CT and PET/CT 1.0 |
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October 1, 2009 |
ACR-SNMMI-SPR Practice Guideline for the Performance of Cardiac Scintigraphy |
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June 14, 2008 |
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June 15, 2002 |
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Endocrine System |
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Date Approved |
Document title |
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September 17, 2011 |
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| October 1, 2009 | ACR-SNMMI-SPR Practice Guideline for the Performance of Parathyroid Scintigraphy |
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October 1, 2009 |
ACR-SNMMI-SPR Practice Guideline for the Performance of Thyroid Scintigraphy and Uptake Measurements |
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September 25, 2006 |
Scintigraphy for Differentiated Papillary and Follicular Thyroid Cancer |
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September 10, 2006 |
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September 5, 2006 |
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Gastrointestinal System |
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Date Approved |
Document title |
| September 29, 2013 | EANM-SNMMI Practice Guideline for Small-Bowel and Colon Transit 1.0 |
| October 1, 2010 | ACR-SNMMI-SPR Practice Guideline for Performance of Gastrointestinal Scintigraphy |
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October 1, 2010 |
ACR-SNMMI-SPR Practice Guideline for the Performance of Liver and Spleen Scintigraphy |
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June 4, 2010 |
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February 8, 2009 |
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June 20, 2003 |
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Genitourinary System |
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Date Approved |
Document title |
| October 1, 2010 | ACR-SNMMI-SPR Practice Guideline for the Performance of Adult and Pediatric Radionuclide Cystography |
| June 20, 2003 | Renovascular Hypertension 3.0 |
General |
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Date Approved |
Document title |
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November 25, 2013 |
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June 8, 2012 |
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October 1, 2011 |
ACR-SNMMI Technical Standard for Diagnostic Procedures Using Radiopharmaceuticals |
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September 12, 2010 |
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June 1, 2007 |
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April 30, 2006 |
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Infection and Inflammation |
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Date Approved |
Document title |
| November 15, 2012 | EANM-SNMMI Guideline for 18F-FDG Use in Inflammation and Infection |
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October 1, 2009 |
ACR-SNMMI-SPR Practice Guideline for the Performance of Scintigraphy for Inflammation or Infection |
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June 2, 2004 |
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June 2, 2004 |
Tc-99m Exametazime (HMPAO)-Labeled Leukocyte Scintigraphy for Suspected Infection/Inflammation 3.0 |
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June 2, 2004 |
In-111 Leukocyte Scintigraphy for Suspected Infection/Inflammation 3.0 |
Skeletal System |
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Date Approved |
Document title |
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June 4, 2010 |
Sodium 18-F Fluoride with PET/CT Bone Scans 1.1 – EANM Endorsement |
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June 20, 2003 |
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Central Nervous System |
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Date Approved |
Document title |
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June 8, 2012 |
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October 26, 2011 |
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February 8, 2009 |
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February 8, 2009 |
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Oncology |
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Date Approved |
Document title |
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September 29, 2013 |
EANM-SNMMI Practice Guideline for Lymphoscintigraphy and Sentinel Node Localization in Breast Cancer |
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July 19, 2011 |
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June 4, 2010 |
Breast Scintigraphy with Breast-Specific Gamma Cameras 1.0 – EANM Endorsement |
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February 11, 2006 |
Procedure Guidelines for Tumor Imaging with 18F-FDG PET/CT 1.0 |
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June 2, 2004 |
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June 15, 2002 |
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Pediatric |
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Date Approved |
Document title |
| October 26, 2010 | Pediatric Dose Consensus Guidelines |
| *Based on the findings of a survey conducted at 13 premier pediatric hospitals in North America indicating administered radiopharmaceutical activities in children varied greatly, a workgroup was established representing the Society of Nuclear Medicine and Molecular Imaging (SNMMI) through the Pediatric Council, the Society for Pediatric Radiology and the Amercian College of Radiology (ACR). The Workgroup achieved concensus on pediatric administered radiopharmaceutical doses for 11 commonly used radiopharmaceuticals. | |
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October 1, 2010 |
ACR-SNMMI-SPR Practice Guideline for the Performance of Adult and Pediatric Radionuclide Cystography |
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October 1, 2009 |
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September 1, 2008 |
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June 20, 2003 |
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January 25, 2003 |
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January 25, 2003 |
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Pulmonary System |
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Date Approved |
Document title |
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July 19, 2011 |
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October 1, 2009 |
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Therapy |
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Date Approved |
Document title |
| June 8, 2012 |
Therapy of Thyroid Disease with Iodine-131 (Sodium Iodide) 3.0 |
| January 25, 2003 | Palliative Treatment for Painful Bone Metastases 3.0 |
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EANM Guidelines |
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SNMMI endorses these guidelines. Dosage recommendations should be taken in the context of “good practice” of nuclear medicine and do not substitute for national and international legal or regulatory provisions. |
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SNMMI Approval Date |
Document title |
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February 7, 2014 |
Lymphoscintigraphy and Sentinel Node Localization in Gynecological Cancers |
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October 28, 2013 |
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September 22, 2012 |
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* MIBG is an unapproved agent in this country and cannot be used in this country unless under an IND as part of an investigational study. |
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March 20, 2012 |
131I/123I- Metaiodobenzylguanidine (MIBG) scintigraphy (2010) |
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March 20, 2012 |
Radioimmunotherapy for B-cell lymphoma with 90Y-radiolabelled itribumomab tiuxetan (Zevalin) (2006) |
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* Pretherapeutic imaging with 111In-ibritumomab tiuxetan is no longer mandatory in the United States. |
Regulatory Issues for EANM GuidelinesApplicable to all countries: Clinicians involved in unsealed source therapy must be knowledgeable about and compliant with all applicable national and local legislation and regulations. Applicable in the United States: The radiopharmaceutical(s) used for the diagnostic and therapeutic procedure(s) addressed in this guideline/guidance document is/are not approved by the Food and Drug Administration (FDA)in the United States. Therefore in the United States, these procedures should be performed only by physicians holding an FDA-approved Investigational New Drug (IND) application for the radiopharmaceutical. |
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Retired Guidelines |
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Please note the below guidelines have been retired and thus not updated since their last approval. Therefore, these guidelines may not reflect current knowledge and practice in the field of nuclear medicine. SNMMI is providing these guidelines on an 'as is' basis for general information purposes only and does not accept any responsibility for accuracy, completeness, currency, relevance, reliability or suitability of the information contained therein. |
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Date Approved |
Document title |
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June 23, 2001 |
Gallium Scintigraphy in the Evaluation of Malignant Disease 3.0 |
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February 7, 1999 |
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February 7, 1999 |
Gastrointestinal Bleeding/Meckel's Diverticulum Scintigraphy 1.0 |
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Guidelines Available for Public Comment |
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As part of the revision or development process, the Committee on SNMMI Guidelines will seek public comment on draft documents in order to ensure we are creating the most accurate guidelines. To submit comments on a guideline, please download the response form and submit to Kendall Horvath via email, k.horvath@snmmi.org. Below are guidelines currently for which we are seeking public input: |
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Comments Due By |
Document title |
| March 28, 2024 | SNMMI Procedure Standard/EANM Practice Guideline for Brain [18F]FDG PET Imaging Version 2.0 Draft |