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New Research: FAPI PET Imaging Superior for Diagnosing Multiple Types of Cancer, with Potential for Targeted Treatment
– May 1, 2023
Two articles in the May issue of JNM illustrate the promise of the novel FAPI radiotracer. Results from the largest study of patients undergoing 68Ga-FAPI PET demonstrate the superiority of 68Ga-FAPI over standard 18F-FDG PET in evaluating multiple types of cancer. In a separate study, a newly designed FAPI-targeted treatment was found to suppress tumor growth in several common cancers in a preclinical setting. These advances have strong potential to provide more precise staging and management for cancer patients.
Newly Developed PSG Score Improves Patient Selection for PSMA Radiopharmaceutical Therapy
– Apr 19, 2023
International, multicenter testing demonstrated the effectiveness of a newly established PSMA PET scoring system that can successfully predict whether metastatic castration-resistant prostate cancer patients will respond to treatment with Lu-177 PSMA therapy. The research was published online in JNM.
JNM Publishes Appropriate Use Criteria for Lymphoscintigraphy in Sentinel Node Mapping and Lymphedema/Lipedema
– Apr 14, 2023
SNMMI and 10 other professional societies have issued appropriate use criteria for lymphoscintigraphy in sentinel node mapping and lymphedema/lipedema. The criteria are summarized in the April issue of JNM.
New Nuclear Medicine Therapy Cures Human Non-Hodgkin Lymphoma in Preclinical Model
– Apr 11, 2023
A single dose of the radioimmunotherapy can cure human non-Hodgkin lymphoma in an animal model, according to research published in the April issue of The Journal of Nuclear Medicine.
Blood-Based Biomarkers Accurately Predict Neuroendocrine Tumor Response to Radiopharmaceutical Therapy
– Apr 6, 2023
A simple blood draw can provide physicians with valuable information about whether PRRT is likely to be effective in a patient with neuroendocrine canceropening new possibilities for tailoring radiopharmaceutical treatment to patients. The research is published in the April issue of JNM.
Molecular Imaging Offers Insight Into Chemo-Brain
– Mar 28, 2023
A new literature review sheds light on how nuclear medicine brain imaging can help evaluate the biological changes that cause chemotherapy-related cognitive impairment (CRCI), commonly known as chemo-brain. This informationpublished ahead-of-print in JNMcan help patients better understand the changes in their cognitive status during and after treatment.
JNM Explores Potential Applications for ChatGPT in Nuclear Medicine and Molecular Imaging
– Mar 27, 2023
In a new JNM article, Irne Buvat, PhD, and Wolfgang Weber, MD, PhD, explore the potential for using AI chatbot ChatGPT in the field of nuclear medicine and molecular imaging.
PSMA PET Improves Decision Making for Prostate Cancer Treatment
– Mar 24, 2023
PSMA PET mapping of cancer recurrence in the prostate bed shows that current radiotherapy contouring guidelineswhich determine the target areas for treatmentmiss a significant number of lesions and may unnecessarily irradiate healthy tissues, according to a new study published ahead of print in JNM. Researchers are calling for redefinition of the guidelines to improve patient outcomes.
New Compact and Low-Cost Lensless Radiomicroscope Developed for Nuclear Medicine Imaging
– Mar 21, 2023
A novel, palm-sized imaging modality that can visualize the distribution of medical radiopharmaceuticals with very fine resolution has been developed and successfully tested, according to research published in March JNM. Known as the lensless radiomicroscope, the instrument offers the same level of imaging performance as its closest imaging equivalent but comes with significantly larger field of view and costs less than $100.
Novel PET Radiotracer Successfully Detects Multiple Cancers, Offers Potential for New Targeted Radionuclide Therapy
– Mar 16, 2023
A new radiotracer, Ga-68 FAP-2286, has been found to be more effective than the most commonly used nuclear medicine cancer imaging radiotracer, F-18 FDG, according to a study published in JNM. Ga-68 FAP-2286 detected 100 percent of primary tumors across multiple cancer types as compared to F-18 FDG, which identified only 80 percent. Ga-68 FAP-2286 was also more effective in detecting lymph node metastases and distant metastases.
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