Clinical Trials Network

The SNMMI Clinical Trials Network provides tools and resources to promote faster, more cost-effective drug development and increase the availability and performance of molecular imaging radiopharmaceuticals for use in the clinic. Increased standardization in trials leads to better data that then results in expanded utilization of radiopharmaceuticals.

The Clinical Trials Network (CTN) was formed in 2008 by SNMMI to help facilitate the effective use of molecular imaging radiopharmaceuticals in clinical trials. Benefits to the drug development industry include access to a database of qualified imaging sites and radiopharmaceutical manufacturers, a robust scanner validation program, access to standardized imaging protocols and clinical research education and training for site personnel. Our Mission is to facilitate the effective use of MI in clinical trials through standardization, coordination, and education for drug development and regulatory approval. A successful scanner validation will ensure that your study patients as well as your clinical patients are being scanned on a quantitatively and quantitatively accurate PET/CT. Click here for more information about our scanner validation program. We also maintain a comprehensive database that stores and manages information on imaging sites, production sites and those sites that have both imaging and production capabilities. To date, we have total of 435 sites registered in the CTN database. To access or add your site to the CTN database, click here. 

DaRT Map

DaRT Color code


Live_meeting_iconMeetings and webinars provide the ideal venue to promote and support standardization in imaging, especially when part of a research trial. The Clinical Trials Network sponsors two major sessions per year during the SNMMI Mid-Winter and Annual Meetings. The CTN Site Orientation and Education Committee and other consultants plan the programs keeping in mind the audience and the ever-evolving landscape of nuclear medicine and molecular imaging. Clinical research basics remain fairly constant but are often not part of the education and training that many molecular imaging personnel receive. To that end, the CTN has developed an outstanding curriculum covering a wide-range of research topics.


CTN 2015 Webinar Series

Register Online | 2015 Webinar Series Descriptions

The CTN serves a unique and critical function in SNMMI. By working closely with sponsors, associations and agencies, CTN members help to advance key initiatives for standardization in PET/CT clinical imaging. The purpose of the internship program is to identify and train future leaders of SNMMI in the structure, governance and operations of the organization; to prepare individuals for progressive levels of responsibility; and to ensure effective leadership that advances the mission and goals of the organization.

Interns serve a two-year term that begins and ends at the SNMMI Annual Meetings. A mentor is appointed by the CTN Leadership for the intern, to work with the intern and supervise special projects and activities. During the two years, the intern is expected to attend the CTN Leadership and Committee meetings at the SNMMI Mid-Winter and Annual Meetings, and participate in conference calls. 

If you are interested is applying for the CTN intern position, please email us at    

Current Intern

Robert FlavellRobert Flavell, MD, PhD (2015-2017)

Dr. Robert Flavell, MD, PhD is the CTN intern for 2015 - 2017. He completed his residency in radiology at the University of California, San Francisco where he is currently a fellow in nuclear medicine. Dr. Flavell’s research interests include radiochemistry, PET radiopharmaceutical development, and hyperpolarized 13C MRI. He plans to spend his time with the CTN assisting the Gallium Users Group in creating a clinical trial protocol and accompanying documents for the development of 68Ga-PSMA, among other projects. We welcome Dr. Flavell to the CTN!



Past Interns  

Lance Burrell_CTN Intern pictureLance Burrell, MS, CNMT, PET, RT(CT) (2013-2015)

Lance Burrell, MS, CNMT, PET, RT(CT) served as the CTN intern from June 2013 to June 2015 while employed as a PET technologist and research assistant in the Department of Radiology at the University of Utah’s Huntsman Cancer Institute (HCI). He continues his journey in the “pursuit of professional fulfillment” where clinical research imaging is a major aspect of his day-to-day responsibilities at HCI. During his internship, Mr. Burrell helped refine methods and practices in improving quality and consistency in research imaging and assisted the Scanner Validation Committee by testing phantoms and reviewing phantom images. He contributed in the development of courses for technologists and presented at SNMMI meetings. We are pleased to have Mr. Burrell continue his involvement in the CTN as an active member of the Education and Scanner Validation Committees. 


Xiaofei WangXiaofei Wang, MD, PhD (2011-2013)  

Xiaofei Wang, MD, PhD, served as a CTN intern for 2011-2013.  As the first CTN intern, Dr. Wang provided valuable assistance with our centralized IND program and acted as a liaison for the CTN with the Chinese Nuclear Medicine Society. When his internship ended, Dr. Wang continued on as a member of the CTN Site Qualification and Monitoring Committee, including reviewing patient images submitted by study sites under our centralized IND for FLT.  




The Clinical Trials Network would like to hear from you.  

We are an organization of molecular imaging experts, from physicians and physicists to scientists and technologists. Many are pioneers in the field of nuclear medicine and molecular imaging. If you need assistance in incorporating molecular imaging into a therapeutic trial or want to study a new radiopharmaceutical, our team of experts can assist you with all phases of a clinical trial. From scanner validation, trial design assistance, and study personnel training, the CTN has programs to ensure that you are utilizing molecular imaging effectively and efficiently. To obtain more information about our specific programs or events, please contact us at

The Clinical Trials Network strives to provide the community with as much information as possible on its projects, programs and overall goals within the context of this website. Often, some questions or topics require additional clarification, which we address through this Frequently Asked Questions page. We realize, however, that there still may be some areas in which the public would like additional information. If your question was not answered on our website or the main SNMMI website, please feel free to submit the question using the link/form below.                    


See All CTN FAQs

Education Program

Scanner Validation Program

Site Qualification and Monitoring

Site Registry - CTN Database

Technologist Resources

Centralized Radiopharmaceutical IND

CTN FAQs Submission Form

CTN logo

CTN works collaboratively with SNMMI Councils and Chapters as well as with external groups to move the entire field forward. In working with other imaging associations such as RSNA, government agencies such as the FDA and industry leaders, the CTN envisions having a key role in advancing the use of radiopharmaceuticals and optimizing the use of molecular imaging in clinical trials and for dissemination into clinical practice.  

Gallium-68 Somatostatin Receptor Agents

Ga-68 DOTATOCGa-68-labeled somatostatin analogs are important imaging agents to detect and manage neuroendocrine tumors (NETs). TheGa-68 Users Group was formed to advance the use of these imaging agents in the US. Members of the Users Group developed harmonized release criteria, an imaging manual, generic data collection forms and a draft informed consent form to aid the community in establishing investigator-sponsored trials. Recently, SNMMI received orphan drug designation for Ga-68 DOTATOC.                                                                                                                                       

  • NEW! Click here to download Ga-68 PSMA-11 Release Criteria
  • Click here to watch lectures from the 3rd Theranostics World Congress on Ga-68 and PRRT.


Press Release



Immune Modulation Therapy and Imaging

CTN co-sponsored a workshop with NCI on Monday, May 2, 2016 titled Immune Modulation Therapy and Imaging: What can we do in clinical trials now? As the workshop chairman Tony Shields, MD, PhD said in his welcome, "immunotherapy clearly is the hottest topic in medical oncology today." But because of the time it takes to see a response in some patients, we have a problem evaluating response to therapy with current imaging strategies. The assembled group of immunologists, imagers, and industry representatives discussed imaging technologies beyond iRECIST (immunotherapy) that could be integrated into trials to measure response. Additionally, the group was charged with identifying markers that will predict response of patients. The goal of the conference was to identify 'shovel-ready' projects that could be added to clinical trials, either NCI- or industry-sponsored, by the end of 2016. 

  • Click here to watch video webcast    
  • Click here to download presentation slides                                                                                                                                                                                                    

NIH R01 Grant - Harmonized PET Reconstructions for Cancer Clinical Trials

This 5-year project, begun in September of 2012, is working to identify and implement harmonized PET reconstruction parameters for all PET/CT scanners for use in clinical trial scenarios where quantitative accuracy is critical. The CTN plays a key administrative role and provides imaging infrastructure to the study group.


News & Other Information

  • NIH has developed a new one-page guide, Why Do Researchers Do Different Kinds of Clinical Studies? Click here to read.
  • NEW! Northern California (Norcal) CarciNET Community's Search Tool/Map for Ga-68 Map


HIGHLIGHTS: Posters-Presentations-Publications

To learn more about the activities of the CTN, explore below.

Posters - CTN submitted posters


Presentations - a selection of research topics


Publications - by and about the CTN