April 15, 2016
Researchers have succeeded in using an imaging technique to record changes and inflammation in the brain of a person with amyotrophic lateral sclerosis (ALS), using a potential biomarker of inflammation. The research, conducted at The Neurological Clinical Research Institute (NCRI) at Massachusetts General Hospital, is part of the TRACK ALS project to identify imaging markers of ALS, so as to facilitate early diagnosis and develop new therapies.
“This is an exciting milestone towards the goal of developing the imaging approach as a readout for inflammation, a critical tool to expedite clinical trials. The study plans to enroll 50 ALS patients and 50 healthy volunteers, and we hope to be able to clearly characterize the role of inflammation in people living with ALS,” Lucie Bruijn, PhD, MBA, chief scientist for the ALS Association, said in an ALS press release.