Appropriate Use Criteria (AUC)

Appropriate Use Criteria (AUC) are statements that contain indications describing when, and how often, an intervention should be performed under the auspices of scientific evidence, clinical judgment, and patient values while avoiding unnecessary provisions of services. SNMMI follows a balanced multidisciplinary approach to guidance development by including various stakeholders in the development process. To view the development process, please click the following link: SNMMI AUC Development Process.

Comments or Questions?

The SNMMI Guidance Oversight Committee is continually developing new Appropriate Use Criteria (AUC) and reviewing and updating existing AUC. If you have specific comments or questions on the content of any of the AUC, or if you have suggestions for new AUC that you feel should be written, please contact the SNMMI Guidance Oversight Committee at All comments will be considered in the AUC development process.



Date Approved

Document Title

September 9, 2017

Somatostatin Receptor PET Imaging in Neuroendocrine Tumors 

June 9, 2017

FDG PET/CT Restaging and Response Assessment of Malignant Disease

June 5, 2017

Hepatobiliary Scintigraphy in Abdominal Pain

January 20, 2017

Ventilation/Perfusion (V/Q) Imaging in Pulmonary Embolism

January 20, 2017

Bone Scintigraphy in Prostate and Breast Cancer

January 28, 2013

Amyloid Imaging

Currently Under Development

PET Myocardial Perfusion Imaging (MPI)

Gastrointestinal Transit

Infection Imaging

Prostate Cancer Imaging

Nuclear Medicine in the Evaluation and Treatment of Thyroid Cancer

To Be Developed in 2018

Renal Imaging

Radium 223


Brain Imaging with HMPO and DAT

Imaging and Therapy of Benign Tumors (including Graves Disease and Radio Iodine Ablation)


Please let us know if you have any suggestions for future topics for AUC development, or any feedback on the existing publications by contacting us at

Available for Public Comment

As part of the development process, the SNMMI Guidance Oversight Committee will seek public comment on draft documents in order to ensure we are creating the most accurate guidelines. To submit comments on an AUC, please download the response form and submit to Below are AUC for which we are currently seeking public input:

Comments Due By

Document Title