Research

With its innovative Clinical Trials Network, influential annual meeting and high-impact journals, SNMMI encourages and facilitates research and science for the nuclear medicine and molecular imaging field. Learn more.

Clinical Trials Network

The Clinical Trials Network (CTN) provides tools and resources to promote faster, more cost-effective drug development and increase the availability and performance of molecular imaging radiopharmaceuticals for use in the clinic. Our Mission is to advance the use of molecular imaging agents in clinical trials through standardization of chemistry and imaging methodology. This includes using imaging radiopharmaceuticals during the course of drug development, as well as bringing new radiopharmaceuticals to regulatory approval. Programs developed over the past 5 years include a comprehensive registry of qualified imaging sites and radiopharmaceutical manufacturers, a robust scanner validation program, access to standardized imaging protocols and a very strong clinical research education curriculum.

LATEST NEWS

  • June 7, 2019New Radiotracer Can Identify Nearly 30 Types of Cancer
    A novel class of radiopharmaceuticals has proven effective in non-invasively identifying nearly 30 types of malignant tumors. Using 68Ga-FAPI PET/CT, researchers were able to image the tumors with very high uptake and image contrast, paving the way for new applications in tumor characterization, staging and therapy. The research is featured in the June issue of The Journal of Nuclear Medicine.
  • May 27, 2019Coronary Artery Disease Diagnosis Improved by Deep Learning Analysis of SPECT MPI
    A multicenter international study has demonstrated that diagnosis of obstructive coronary artery disease can be improved through deep learning analysis of SPECT myocardial perfusion imaging. The research is featured in the May issue of The Journal of Nuclear Medicine.
  • April 29, 2019Nuclear Medicine Therapy Shows Long-Term Effectiveness for Malignant Neuroendocrine Tumors
    A 12-year retrospective clinical study of patients who received peptide receptor radionuclide therapy for malignant neuroendocrine tumors demonstrates the long-term effectiveness of this treatment, which also allows patients to maintain a high quality of life. The study is featured in the April issue of The Journal of Nuclear Medicine.
  • April 8, 2019SNMMI and ACR Collaborate on Clinical Data Registry for Nuclear Medicine
    SNMMI and the American College of Radiology announce a new collaborative clinical data registry to support high-quality practice and patient care. The registry will allow collection and analysis of data on nuclear medicine procedures, supporting continuous improvement of patient care.
  • April 4, 2019New PET Imaging Biomarker Could Better Predict Progression of Alzheimer’s Disease
    Researchers have discovered a way to better predict progression of Alzheimer’s disease. A study utilizing positron emission tomography to image microglial activation levels showed that these levels could predict current and future cognitive performance better than beta-amyloid levels. The research is published in the April issue of The Journal of Nuclear Medicine.
  • March 29, 2019First Total-Body PET/CT Studies Show Potential for Better, Faster, Lower-Dose Images
    The first human case studies from the first total-body PET/CT scanner show enhanced image quality, reduced scan time, a longer time window to perform the scan, reduced dose and total-body dynamic imaging, among other benefits and possibilities. The research is published in the March issue of The Journal of Nuclear Medicine.
  • March 11, 2019New Tracers Improve Diagnosis of Cancer and May Be Useful for Treatment
    Researchers have identified two new nuclear medicine tracers that make it easier to diagnose and potentially treat multiple types of cancer, providing high-quality images with less patient preparation and shorter acquisition times.
  • March 5, 2019Nuclear Medicine Imaging Monitors Effectiveness of Therapy for Melanoma Patients
    Nuclear medicine imaging with PET/CT can monitor the effectiveness of immunotherapy treatment for metastatic melanoma and predict outcome. In this way, a patient’s therapy can be more effectively tailored to his or her personal response.

Preclinical Imaging

CMIIT’s mission is to engage the molecular imaging community and leverage the SNMMI infrastructure to advance the adoption of emerging molecular imaging technologies and probes in preclinical and clinical applications. One of the goals is to develop educational resources for a “translational researcher”. CMIIT will provide researchers with needed education and training on the “nuts and bolts” of translating and transitioning an agent or technique from pre-clinical research into the clinical practice such as tracer development, equipment, and funding.

The Nuclear Medicine Clinical Trial Group, LLC

Under the auspices of the Society of Nuclear Medicine and Molecular Imaging, the Nuclear Medicine Clinical Trial Group(NMCTG) assists industry partners and academic investigators in managing clinical research activities.  Its goals include ensuring quality imaging is conducted in drug or diagnostic clinical trials and providing training for molecular imaging professionals performing clinical research. Many of the programs established under the Clinical Trials Network, such as its robust Education Program, provide support to the NMCTG to help carry out its mission.