A) Perfusion polar maps of SPECT-MPI at stress and rest show largely reversible anteroapical perfusion defect. (B) 3D volume-rendered CTA images show coronary vessel tree with stenosis of mid LAD and proximal stenosis of first diagonal branch. (C) Fused 3D SPECT/CT images are able to identify stenosis as functionally relevant lesions. (D) Findings were confirmed by coronary angiography.
SPECT involves the use of an imaging device (a gamma camera) and a radiotracer that is injected into the patient’s bloodstream and accumulates in a target organ or attaches to specific cells. As the camera rotates around the patient, it detects the radiotracer and creates three-dimensional images that show how it is distributed in the body. This distribution pattern reveals information on blood flow and how organs and tissues are functioning.
SPECT imaging is often fused with three-dimensional images of the heart produced by MPI to reveal the flow of blood through the coronary arteries and the heart itself.