July 10, 2013
Differentiated thyroid carcinoma (DTC) patients typically undergo thyroidectomy followed by therapeutic I-131 as the normal course of treatment, but not all DTC lesions respond to therapy. FDG PET/CT detected additional tumors in up to 46 percent of certain patients when performed concurrently with I-131 therapy. The method could help improve risk stratification for these patients by catching outlier lesions, according to a study published June 24 in the Journal of Nuclear Medicine .
Jeong Won Lee, MD, PhD, from the department of nuclear medicine at Yonsei University College of Medicine in Seoul, and colleagues conducted a retrospective study of 286 DTC patients at two medical centers to evaluate F-18 FDG PET/CT as a complement to I-131 therapy for patients with intermediate to high risk or remaining or recurrent disease.