PET/optical combo can guide breast-conserving surgery

June 12, 2017

Researchers are reporting early success in the combination of optical and molecular imaging to view FDG-PET images that detect early-stage breast cancer. The technique, known as Cerenkov luminescence imaging (CLI), can assess tumor margins during breast tumor surgery by detecting light emitted from an FDG-PET radiopharmaceutical.

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If validated clinically, CLI could become the first option rather than breast-conserving surgery, which is currently the most widely chosen initial treatment, according to Dr. Arnie Purushotham, chair of breast cancer and professor at King's College London, and colleagues (Journal of Nuclear Medicine, June 2017, Vol. 58:6, pp. 891-898).

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