New PET image analysis technique tracks amyloid changes with greater power

March 19, 2015

Researchers from Banner Alzheimer's Institute (BAI) have developed a new brain image analysis method to better track the progression of beta-amyloid plaque deposition, a characteristic brain abnormality in Alzheimer's disease, according to a study published in the March issue of The Journal of Nuclear Medicine. Investigators also believe this new approach may make it easier to evaluate investigational anti-amyloid treatments in clinical trials.

During the last decade, researchers have been using positron emission topography (PET) to assess amyloid plaque deposition in patients with clinical symptoms of Alzheimer's and in cognitively normal persons at risk for the disease. They also have been using it to assess the ability of investigational treatments to slow the further accumulation of amyloid or remove plaques that already exist.

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