Revolution in Imaging Tech Brings Heart Failure Molecule Into View

February 4, 2015

Using the same technology that made smartphone cameras possible, scientists at Columbia University Medical Center are capturing images of individual molecules at a level of detail never before possible—including images of a molecule implicated in heart disease and muscle diseases.

The new images of the ryanodine receptor—a membrane protein that functions as a channel for the passage of calcium ions in muscle cells —have led to the determination of its 3-D structure. Defects in the ryanodine receptor can lead to heart failure, age-related muscle weakness, and muscular dystrophy.

Read the full story.