Archive

Molecular Imaging Bibliography

The following list of research and review papers was compiled by members of the CMIIT Communications Task Force. It is designed to serve as a resource for students, researchers, and educators. Nominations for additional articles to be included in this resource are welcomed and may be sent to mimage@snm.org.

For references specific to optical imaging, see the Optical Imaging Bibliography.

For references specific to brain imaging, please see Key Amyloid Imaging References.

General molecular imaging

• Contag CH. In Vivo Pathology:Seeing with Molecular Specificity and Cellular Resolution in the Living Body. Annual Review of Pathology: Mechanisms of Disease. 2007;2:277–305.
• Jaffer FA, Weissleder R. Molecular imaging in the clinical arena. Journal of the American Medical Association. 2005;293:855–862 .
• Massoud T, Gambhir, SS. Integrating noninvasive molecular imaging into molecular medicine: an evolving paradigm. Trends in Molecular Medicine. 2007;13:183–191.
• Massoud TF, Gambhir SS. Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes and Development. 2003;17:545–580.
• Miller J, Thrall J. Clinical molecular imaging. Journal of the American College of Radiology. 2004;1(suppl 1):4–23.
• Weissleder R, Mahmood U. Molecular Imaging. Radiology. 2001;219:316–333.
• Weissleder R, Ntziachristos V. Shedding light onto live molecular targets. Nature Medicine. 2003;9:123–128.
• Concepts and Strategies for Molecular Imaging, Chemical Reviews. 2010(4)110:2575-3298.

Imaging cancer

• Gambhir SS. Molecular imaging of cancer with positron emission tomography. Nature Reviews Cancer. 2002;2:683–693
• Mankoff DA, Eary JF, Link JF, et al. Tumor-specific PET imaging in patients: FDG and beyond. Clinical Cancer Research. 2007;13:3460–9.
• Mankoff DA, et al. Molecular imaging research in the outcomes era: measuring outcomes for individualized cancer therapy. Academic Radiology. 2007;14:398–405.
• Molecular Imaging of Cancer: From Molecules to Humans. Gambhir SS, editor, Journal of Nuclear Medicine. 2008;49:Suppl 2.
• Weissleder R. Molecular imaging in cancer. Science. 2006;312:1168–1171.
• Weissleder R. Scaling down imaging: Molecular mapping of cancer in mice. Nature Reviews Cancer. 2002;2:11–18.
• Weissleder R, Pittet MJ. Imaging in the era of molecular oncology. Nature. 2008;452:580–589.
• Wester H-J. Nuclear imaging probes:from bench to bedside. Clinical Cancer Research. 2007;13:3470–3481.

Cardiovascular molecular imaging

• Wu JC, Bengel FM, Gambhir SS. Cardiovascular molecular imaging. Radiology. 2007;244:337–55.

Imaging gene expression

• Gross S, Piwnica-Worms D. Spying on Cancer:Molecular Imaging in vivo with genetically encoded reporters. Cancer Cell. 2005;7:5–15.
• Gross S, Piwnica-Worms D. Veni, Vidi, Vici: In Vivo Molecular Imaging of Immune Response. Immunity. 2007;27:533–538.
• Herschman HR. Noninvasive imaging of reporter gene expression in living subjects. Advances in Cancer Research. 2004:92;29–80.
• Villalobos V, Naik S, Piwnica-Worms D. Current State of Imaging Protein-Protein Interactions In Vivo with Genetically Encoded Reporters. Annual Review of Biomedical Engineering. 2007;9:321–349.

Molecular imaging and drug development

• Gross S, Piwnica-Worms D, Molecular imaging strategies for drug discovery and development. Current Opinion in Chemical Biology. 2006;10:334–342.
• Hargreaves RJ. The role of molecular imaging in drug discovery and development. Clinical Pharmacology and Therapeutics. 2008;83:349–353.
• Rudin M, Weissleder R. Molecular Imaging in Drug Discovery and Development. Nature Reviews Drug Discovery. 2003;2:123–131.
• Willman JK, van Bruggen N, Dinkelborg LM, Gambhir SS. Molecular imaging in drug development. Nature Reviews Drug Discovery. 2008;7:591–607.

Instrumentation and methods

• Cherry SR. In vivo molecular and genomic imaging: new challenges for imaging physics. Physics in Medicine and Biology. 2004;49:R13–R48.
• Cherry SR. Multimodality in vivo imaging systems: Twice the power or double the trouble? Annual Review of Biomedical Engineering. 2006;8:35–62.
• Koo V, Hamilton P, Williamson K. Non-invasive in vivo imaging in small animal research. Cellular Oncology. 2006;28:127–139.
• Lecchi M, et al. Instrumentation and probes for molecular and cellular imaging. Quarterly Journal of Nuclear Medicine and Molecular Imaging. 2007;51:111–26.
• Levin CS, Primer on molecular imaging technology. European Journal of Nuclear Medicine and Molecular Imaging. 2005;32(suppl 2):S325–S345.
• Lyons, SK. Advances in imaging mouse tumour models in vivo. Journal of Pathology. 2005;205:194–205.
• Margolis DJA, Hoffman JM, Herfkens RJ, Jeffrey RB, Quon A, Gambhir SS. Molecular Imaging Techniques in Body Imaging. Radiology. 2007, 245:333–356.
• Meikle SR, Kench P, Kassiou M, R Banati RG. Small animal SPECT and its place in the matrix of molecular imaging technologies, Physics in Medicine and Biology. 2005;50:R45–R61.
• Ntziachristos V. Fluorescence molecular imaging. Annual Review of Biomedical Engineering. 2006;8:1–33.
• Park JM, Gambhir SS. Multimodality radionuclide, fluorescence, and bioluminescence small-animal imaging. Proceedings of the IEEE. 2005;3:771–783.
• Rao JH, Dragulescu-Andrasi A, Yao, HQ, et al. Fluorescence imaging in vivo: recent advances. Current Opinion in Biotechnology. 2007;18:17–25.
• Shaner NC, Stienbach PA, Tsien RY. A guide to choosing fluorescent proteins. Nature Methods. 2005,2:905–909.
• Thorne SH, Contag CH. Using in vivo bioluminescence imaging to shed light on cancer biology. Proceedings of the IEEE. 2005;93:750–762.