SNMMI Statement: Possible Effect of Omicron Infection on FDG PET/CT Scans

January 14, 2022

As a professional society representing more than 16,000 nuclear medicine professionals, it is SNMMI’s responsibility to distribute information relevant to the evolving COVID-19 pandemic to our members as we navigate through various ups and downs of each successive wave. Over the past 18 months, the SNMMI COVID-19 Task Force has met bi-weekly to monitor, support, educate, and provide guidance to the nuclear medicine and molecular imaging community. 

The Task Force members have recently observed an unusual imaging pattern on FDG PET/CT or FDG PET/MR that may be due to COVID-19 infection.

Unlike the FDG PET/CT pattern seen with infections from previous strains of COVID-19, with principal involvement of the lungs, this new array of findings is primarily centered in the upper aerodigestive tract and cervical lymph nodes. Specifically, there is prominent, symmetric FDG uptake throughout the nasopharynx, oropharynx and tonsils with or without associated FDG-avid cervical lymphadenopathy, particularly in the suprahyoid neck. Based on what we know about the Omicron variant, it is conceivable that this pattern, whenever correlated with COVID-19 infection, is a result of the presently dominant Omicron strain. 

The Task Force recommends that this pattern should be taken into consideration at the time of FDG PET/CT interpretations and the possibility of infection with Omicron variant of COVID-19 should be entertained in the differential diagnosis. Since this pattern can by no means be diagnostic of COVID-19 infection, the Task Force makes the following recommendations.

1. Check the patient records to see if there is a recent positive COVID-19 test.
2. Determine if the patient is at higher risk of COVID-19 infection based on current symptoms or due to recent exposure or travel. If so, a recommendation can be made to test for COVID-19 in the appropriate setting.
3. Compare with prior FDG PET/CT examinations and the patient’s history to determine if this represents chronic inflammatory/reactive process or stable malignancy such as lymphoma.
4. Various differential diagnostic possibilities should be considered if this pattern is new or if there is interval progression including, but not limited to, infection with COVID-19, other viruses such as Epstein-Barr virus, malignancy and bacterial infections.
5. This pattern may also be seen in children and younger adults but should be interpreted cautiously in view of normal increased activity that can be physiologic. Correlation with history and symptoms and comparison to prior examinations is recommended.

 

 

Nuclear Medicine–Specific Information

NOTE: See next tab for recent articles on nuclear medicine and COVID-19.

COVID Forum

• SNMMI COVID Discussion Forum
  Post a question or see what your colleagues are discussing in this SNMMI all-member community forum.

Nuclear Medicine Used for COVID

• Radioimmunotherapy may help treat COVID-19 (June 16) 
  Monopar Therapeutics and NorthStar Medical Radioisotopes have announced a collaboration to develop potential radioimmunotherapeutics to treat severe COVID-19.

Nuclear Medicine Webinars

• Managing Seasonal Burnout in the Age of COVID-19
  December 16, 2021 (recording)
• NCRP-NCI Workshop on LDRT for COVID Treatment: A Report
  October 8, 2020 (coming soon)
• Tempest in a Nebulizer – Lung Scans in the Era of COVID-19 
  Also available with CE credit (September 30, 2020 – recording)
• COVID-19 antibody tests and the UK Rapid Testing Consortium
  June 18, 2020 (recording)
• FDA Town Hall: Impact of COVID-19 on Regulatory Activities
  June 17, 2020 (video, slide deck, Q&As)
• How Should Nuclear Medicine Departments Prepare to Return to Normal (Academic Institution) 
  Also available with CE credit (May 15, 2020)
• NRC/SNMMI Town Hall – Regulatory Relief and Questions from the Nuclear Medicine Community 
  Also available with CE credit (May 13, 2020)
• COVID-19: Transitioning to a 'New-Normal' When and How 
  May 13, 2020 (recording)
• SNMMI-TS Virtual Town Hall: What Are You Experiencing re: COVID-19 in Your Area?
  (May 7, 2020)
• Imaging of a COVID-19–Positive Patient: What to Expect
  April 29, 2020 (Recording)
• IAEA Webinar Summary (April 28, 2020)
• COVID-29 Pandemic: Supply of Medical Radioisotopes and Radiopharmaceuticals (IAEA)
  April 23, 2020 (Recording)
• COVID-19 Pandemic: Guidance for Nuclear Medicine Departments (IAEA)
  April 16, 2020 (Recording)
• Coronavirus Disease (COVID-19) Pandemic: Challenges for the Nuclear Medicine Departments (IAEA)
  March 25, 2020 (Recording)
  

SNMMI COVID-19 Industry Partners Satellite Symposium Webinars

• How Nuclear Medicine May Help in (or serve for) the Diagnostic and Monitoring of COVID-19 Patients 
  May 28, 2020 (Recording)
  Presented by: Spectrum Dynamics
• Imaging From Home, Can it be Better? 
  June 4, 2020 (Recording)
  Presented by: MIM Software

Vaccination Recommendation 

• SNMMI COVID-19 Task Force Vaccination Recommendation (June 2021)
  To ensure the health and safety of our family, friends, colleagues and patients, the SNMMI COVID-19 Task Force strongly urges all eligible SNMMI members and healthcare professionals to be vaccinated as soon as possible.

Nuclear Medicine Guidelines

• SNMMI Statement: Possible Effect of Omicron Infection on FDG PET/CT Scans (January 2022)
  SNMMI's COVID-19 Task Force members have recently observed an unusual imaging pattern on FDG PET/CT or FDG PET/MR that may be due to COVID-19 infection.
• SNMMI Statement: COVID-19 and Ventilation/Perfusion (V/Q) Lung Studies (September 2021)
  SNMMI has issued a newly updated statement on V/Q lung studies reflecting the significant developments in the COVID epidemic.
• SNMMI Statement: The Effect of COVID-19 Vaccination on FDG PET/CT (March 2021)
  FDG-avid reactive lymphadenopathy on PET/CT has been reported in patients following COVID-19 vaccinations. SNMMI's COVID-19 Task Force makes recommendations based on the currently available information.
• COVID-19 Pandemic: Technical Guidance for Nuclear Medicine Departments (July 2020)
  Published by the IAEA
• The American College of Nuclear Medicine Guidance on Operating Procedures for a Nuclear Medicine Facility During COVID-19 Pandemic (May 1, 2020)
  Specialty-centered guidance from ACNM for nuclear medicine facilities during the COVID-19 epidemic/pandemic.
• Guidance and Best Practices for Nuclear Cardiology Laboratories during the Coronavirus Disease 2019 (COVID-19) Pandemic: An Information Statement from ASNC and SNMMI (JNM, June 2020)
  In this Information Statement, SNMMI and the American Society of Nuclear Cardiology (ASNC) address the practice of nuclear cardiology in the setting of the current COVID-19 pandemic, reflecting the perspectives of diverse practices across the United States and worldwide.
• COVID-19 pandemic: guidance for nuclear medicine departments (April 15, 2020)
  IAEA guidelines to help nuclear medicine departments adapt operating procedures to minimize the risk of COVID-19 infections among patients, staff and the public.

COVID-Related Advocacy

• SNMMI Requests Regulatory Relief for Training for Imaging and Localization Studies (June 11, 2020) 
  SNMMI, ASNC, ASTRO and ACR requested regulatory relief for training for imaging and localization studies during the COVID-19 Public Health Emergency.
• SNMMI Advocates for Access to Diagnostic Radiopharmaceuticals through COVID-19 and Beyond (May 15, 2020) 
• SNMMI Advocates for Frontline Healthcare Workers (May 8, 2020)
  SNMMI joined various other medical professional societies in advocating for all frontline members of the healthcare delivery system during the COVID-19 pandemic
• SNMMI Encourages Legislators To Ensure Accessibility to PPE (March 26, 2020)
  SNMMI joined other diagnostic imaging societies in calling on the president of the United States to ensure an adequate supply of personal protective equipment.
• See also Government Resources and Other Resources tabs.

Radioisotope Supply

• NMEu: Update on Global Supply of Mo-99 (May 29, 2020)
  The situation has largely normalized; a few difficulties still in transportation to Mexico and South America.
• NMEu: COVID-19 and the Global Supply of Mo-99 (May 11, 2020)
• NMEu: COVID-19 and the Global Supply of Mo-99 (April 27, 2020)
• Medical Radioisotopes still Produced but Facing Distribution Challenges Globally (April 20, 2020)
  IAEA: The production of radioisotopes used in medicine has continued during the COVID-19 pandemic, but hospitals could face shortages due to bottlenecks in transport and distribution.
  
• NMEu: COVID-19 and the Global Supply of Mo-99 (April 15, 2020)
  Production continues normally within adjustments for COVID-19. Logistics difficulties create risk, but no specific shortages are presently foreseen.

Ventilation/Perfusion (V/Q) Studies

• SNMMI Statement: COVID-19 and Ventilation/Perfusion (V/Q) Lung Studies (September 2021)
  SNMMI has issued a newly updated statement on V/Q lung studies reflecting the significant developments in the COVID epidemic.
• Lung Scintigraphy in the Era of COVID-19 and Chronic Thromboembolic Pulmonary Hypertension (May 8, 2020) 
  This article discusses two recent developments related to lung scintigraphy: the coronavirus disease 2019 (COVID-19) pandemic and the increase in requests for lung ventilation/perfusion scintigraphy for the diagnosis and management of chronic thromboembolic pulmonary hypertension.
  

The Journal of Nuclear Medicine (JNM) 

COVID-19 mRNA Vaccination: Age and Immune Status and Its Association with Axillary Lymph Node PET/CT Uptake (January 2022)
Michal Eifer, Noam Tau, Yousef Alhoubani, Nayroz Kanana, Liran Domachevsky, Jala Shams, Nir Keret, Malka Gorfine and Yael Eshet

Absolute lymphocyte count after COVID-19 vaccination is associated with vaccine-induced hypermetabolic lymph nodes on ¹⁸F-FDG PET/CT: a focus in breast cancer care (ahead of print Dec 2021)
Romain-David Seban, Capucine Richard, Camila Nascimento-Leite, Jerome Ghidaglia, Claire Provost, Julie Gonin, Christophe Le Tourneau, Emanuela Romano, Nicolas Deleval and Laurence Champion

Imaging in Post-COVID Lung Disease (PCLD): does [¹⁸F]-FDG-PET/CT have the Key? (ahead of print October 2021)
Olivier Gheysens, Leïla Belkhir and François Jamar

Lung scintigraphy for pulmonary embolism diagnosis in COVID-19 patients: a multicenter study (ahead of print October 2021)
Pierre-Yves Le Roux, Pierre-Benoit Bonnefoy, Achraf Bahloul, Benoit Denizot, Bertrand Barres, Caroline Moreau-Triby, Astrid Girma, Amandine Pallardy, Quentin Ceyrat, Laure Sarda-Mantel, Micheline Razzouk-Cadet, Reka Zsigmond, Cachin Florent, Gilles Karcher and Pierre-Yves Salaun

Neuropsychological Profiles and Cerebral Glucose Metabolism in Neurocognitive Long COVID-syndrome (Ahead of print Oct 2021)
Andrea Dressing, Tobias Bormann, Ganna Blazhenets, Nils Schroeter, Lea I Walter, Johannes Thurow, Dietrich August, Hanna Hilger, Katarina Stete, Kathrin Gerstacker, Susan Arndt, Alexander Rau, Horst Urbach, Siegbert Rieg, Dirk Wagner, Cornelius Weiller, Philipp T Meyer and Jonas A Hosp

¹⁸F-FDG–Avid Axillary Lymph Nodes After COVID-19 Vaccination (October 2021)
B. Jake Johnson, Kathryn M. Van Abel, Daniel J. Ma and Derek R. Johnson

Postinfectious Neurologic Complications in COVID-19: A Complex Case Report (August 2021)
Pietro Tiraboschi, Rubjona Xhani, Simone M. Zerbi, Angelo Corso, Isabella Martinelli, Laura Fusi, Giampiero Grampa, Andrea Lombardo, Paola Cavalcante, Cristina Cappelletti, Francesca Andreetta, Alberto Sironi, Alberto Redolfi and Cristina Muscio

Experience with a perfusion-only screening protocol for evaluation of pulmonary embolism during the COVID-19 pandemic surge (ahead of print August 2021)
Arun Kumar, Renee M. Moadel, Linda B. Haramati, Kenny Ye, Leonard M. Freeman and Lionel S. Zuckier

Lessons learned from post-COVID-19 vaccination PET/CT studies (ahead of print July 2021)
Marina Orevi, Alexandre Chicheportiche and Simona Ben-Haim

Evolution of ¹⁸F-FDG-PET/CT findings in patients following COVID-19 pneumonia: An Initial Investigation (ahead of print July 2021)
Andrew Thornton, Francesco Fraioli, Simon Wan, Helen S Garthwaite, Balaji Ganeshan, Robert Ian Shortman, Raymond Endozo, Stefan Voo, Irfan Kayani, Deena Neriman, Leon Menezes, Jamshed B. Bomanji, Toby Hillman, Melissa Heightman, Joanna C Porter and Ashley M Groves

Low but Evident Recovery from Neocortical Dysfunction and Cognitive Impairment in a Series of Chronic COVID-19 Patients (July 2021)
Ganna Blazhenets, Nils Schroeter, Tobias Bormann, Johannes Thurow, Dirk Wagner, Lars Frings, Cornelius Weiller, Philipp T. Meyer, Andrea Dressing and Jonas A. Hosp

V/Q SPECT/CT in the Time of COVID-19: Changing the Order to Improve Safety Without Sacrificing Accuracy (July 2021)
Wolfgang M. Schaefer, D. Knollmann and Philipp T. Meyer

Oncology-inspired treatment options for COVID-19  (December 2020)
NagaVaraKishore Pillarsetty, Lukas Carter, Jason S. Lewis, and Thomas Reiner

Guidance and best practices for reestablishment of non-emergent care in nuclear cardiology laboratories during the coronavirus disease 2019 (COVID-19) pandemic: An information statement from ASNC, IAEA, and SNMMI (October 2020)

Hicham Skali, Venkatesh L. Murthy, Diana Paez, Elisa M. Choi, Felix Y.J. Keng, McGhie A. Iain, Mouaz Al-Mallah, Roxana Campisi, Timothy M. Bateman, Ignasi Carrio, Rob Beanlands, Dennis A. Calnon, Vasken Dilsizian, Maurizio Dondi, Alessia Gimelli, Robert Pagnanelli, Donna M. Polk, Prem Soman, Andrew J. Einstein, Sharmila Dorbala, and Randall C. Thompson

Global Impact of COVID-19 on Nuclear Medicine Departments: An International Survey in April 2020  (September 2020)
Lutz S. Freudenberg, Diana Paez, Francesco Giammarile, Juliano Julio Cerci, Moshe Modiselle, Thomas N.B. Pascual, Noura El-Haj, Pilar Orellana, Ignasi Carrio, Stefano Fanti, Cristina Sebastiao Matushita, Yaroslav Pynda, and Ken Herrmann

The Impact of COVID‐19 on the Health‐Care Workforce: From Heroes to Zeroes? (August 2020)
Johannes Czernin

Peptide Receptor Radionuclide Therapy (PRRT) During the COVID-19 Pandemic: Are There Any Concerns?  (August 2020) Lisa Bodei, Emily K. Bergsland, Wouter K. de Herder, Diego Ferone, Rodney J. Hicks, Thomas A. Hope, Jolanta A. Kunikowska, Marianne Pavel, Diane L Reidy-Lagunes, Jens Siveke, Jonathan R. Strosberg, Ulf Dittmer and Ken Herrmann

Overcoming the COVID-19 Crisis and Planning for the Future (August 2020)
Steven H LoGiudice, Allison Liebhaber, and Heiko Schöder

COVID-19 and Pulmonary Embolism: Diagnostic Imaging Trends (August 2020) 
Sedighe Karimzadeh, Akshay Raut, and Huy Nguyen Tien

Guidance and Best Practices for Nuclear Cardiology Laboratories During the Coronavirus Disease 2019 (COVID-19) Pandemic: An Information Statement from ASNC and SNMMI (June 2020)
Hicham Skali, Venkatesh L. Murthy, Mouaz H. Al-Mallah, Tim M. Bateman, Rob Beanlands, Nathan Better, Dennis A. Calnon, Vasken Dilsizian, Alessia Gimelli, Robert Pagnanelli, Donna M. Polk, Prem Soman, Randall C. Thompson, Andrew J. Einstein, and Sharmila Dorbala

Yttrium-90 Radioembolization: Telemedicine During the COVID-19 Outbreak, Opportunity for Prime Time (June 2020)
Lawrence Han Hwee Quek, Anbalagan Kannivelu, and Uei Pua

The role of Nuclear Medicine for COVID-19 – Time to Act Now (June 2020)
Freimut D Juengling, Antonio Maldonado, Frank Wuest, and Thomas Hellmut Schindler

Dr. Li Wenliang and the Time of COVID-19 (May 2020)
Johannes Czernin

Nuclear Medicine Operations in the Times of COVID-19: Strategies, Precautions and Experiences (May 2020)
Johannes Czernin, Stefano Fanti, Philipp T. Meyer, Martin Allen-Auerbach, Marcus Hacker, Mike Sathekge, Rodney Hicks, Andrew M. Scott, Jun Hatazawa, Mijin Yun, Heiko Schöder, Peter Bartenstein, and Ken Herrmann

Incidental Findings Suggestive of COVID-19 in Asymptomatic Patients Undergoing Nuclear Medicine Procedures in a High Prevalence Region (May 2020)
Domenico Albano, Francesco Bertagna, Mattia Bertolia, Giovanni Bosio, Silvia Lucchini, Federica Motta, Maria Beatrice Panarotto, Alessia Peli, Luca Camoni, Frank M. Bengel, and Raffaele Giubbini

Diagnostic Evaluation of Pulmonary Embolism During the COVID-19 Pandemic (May 2020)
Lionel S. Zuckier, Renée M. Moadel, Linda B. Haramati, and Leonard Freeman 

Journal of Nuclear Medicine Technology (JNMT) 

¹⁸F-Fluciclovine Avid Axillary Lymph Nodes After COVID-19 Vaccination on PET/CT for Suspected Recurrence of Prostate Cancer (ahead of print December 2021)
Justin G Peacock, Elisabeth A Banks and Nathan E McWhorter

Lung Perfusion Scintigraphy Early After COVID-19: A Single-Center Retrospective Study (December 2021)
De Sajal, Ravina Mudalsha, Lukose Tinu, T. Ganga Ranganath and Sahu Dibakar

The Impact of Covid-19 on First Year Undergraduate Nuclear Medicine Students' Practical Skills Training (ahead of print November 2021)
Melissa Shields and Helen Warren-Forward

Reactive Axillary Lymphadenopathy to COVID-19 Vaccination on ¹⁸F-FDG PET/CT (September 2021)
Mathew V. Smith and Ming Yang

Effect of COVID-19 on ¹⁸F-FDG PET/CT: Is There a Need to Consider COVID-19 Status Before Planning ¹⁸F-FDG PET/CT for Oncologic Evaluation? (September 2021)
Anwin Joseph Kavanal, Santosh Ranjan Jena, Rajender Kumar, Chandan Krushna Das, Sunil Kumar and Bhagwant Rai Mittal

Infection Prevention in the Era of COVID-19: 2021 Basic Procedure Review (June 2021)
Barbara J. Jara

Intramuscular Injections for COVID-19 Vaccinations (Practical Protocol Tip – March 2021)
Kathy S. Thomas

COVID-19 Vaccination: An Overview and Education Tool for Nuclear Medicine Technologists (March 2021)
L. Harold Barnwell and Mark H. Crosthwaite

Guidelines on Setting Up Stations for Remote Viewing of Nuclear Medicine and Molecular Imaging Studies During COVID-19 (March 2021)
Jerold W. Wallis, Ran Klein, Tyler J. Bradshaw, Ciprian Catana, Mathieu Hatt, Richard Laforest, Chi Liu, Osama Mawlawi, Keisha C. McCall, Dustin R. Osborne, Jing Tang, R. Glenn Wells and Munir Ghesani

Nuclear Medicine Clinical Practice in the United States During the COVID-19 Era and Beyond (September 2020)
Gail A. McFarland and Sara G. Johnson

Post–COVID-19 New Normal for Molecular Imaging Departments: A United Kingdom Perspective (September 2020)
Jessica Williams, Emma Meadows, and Manrita Singh

Post–COVID-19 New Normal for Nuclear Medicine Practice: An Australasian Perspective (September 2020) 
Geoff Currie

Coronavirus (COVID-19) Pandemic: What Nuclear Medicine Departments Should Know (June 2020) 
Gopinath Gnanasegaran, Hian Liang Huang, Jessica Williams, and Jamshed Bomanji

From One Technologist to Another – COVID-19 Questions Answered (June 2020) 
Dmitry D. Beyder, Mark H. Crosthwaite, James Crowley, Lyndsi M. Hay, Kimberly Kerrylin Jackson, Nancy McDonald, Lynne T. Roy, Tricia Peters, and Nikki Wenzel-Lamb

Divide and Conquer: Strategies to Manage a Nuclear Medicine Department during COVID‐19 (June 2020)
Wei Y Tham, Aaron KT Tong, Kelvin SH Loke, Liyi Chio, Gabriel KY Lim, Xin Y Seah, David CE Ng, Sean XX Yan, Winnie WC Lam

Uptake

Lung Scintigraphy in the Era of COVID-19 and Chronic Thromboembolic Pulmonary Hypertension (May 8)
J. Anthony Parker, MD, PhD, and Kevin J. Donohoe, MD

Training and Certification

American Association of Physicists in Medicine

• All AAPM in-person meetings, plans for AAPM funded travel and meetings of other groups at HQ are to be canceled through April 30, 2020. Find more information here.
  
• Update for graduate program directors regarding recent developments in graduate medical physics education in response to the COVID-19 pandemic. (March 18)

American Board of Medical Specialties (ABMS)

• ABMS reaffirms support for physicians to focus their priorities on patients, families, and the communities they serve. (March 26)

American Board of Nuclear Medicine (ABNM)

• NM Program Directors: COVID-19 Impact on Nuclear Medicine Training Programs (March 25, 2020)
• Diplomates: COVID-19 and Adjustments to CertLink (March 24, 2020)
• NM Program Directors: Modification of ABNM Leave Policy for COVID-19 (March 12, 2020)

American Board of Radiology 

• Coronavirus Information

American Board of Science in Nuclear Medicine

• The ABSNM currently plans to give the General and Specialty Examinations as scheduled on June 12, 2020 in New Orleans, Louisiana. See more updates here.

American Registry of Radiologic Technologists (ARRT)

• ARRT COVID-19 Update: ARRT is closely monitoring the COVID-19 pandemic and how it could affect students and RTs. RTs who have questions related to their postprimary eligibility pathway requirements, renewals, CQR, or other issues should log on to their online accounts first to see if they’ve received an update specific to their concerns.  

American Society of Radiologic Technologists (ASRT)

• COVID-19 Resources for Radiologic Technologists and Students: ASRT is closely monitoring the COVID-19 situation. ASRT is providing resources to help radiologic technologists and students adapt to this challenge.

JRCNMT

• The JRCNMT is closely monitoring the latest information regarding the COVID-19 virus and considering its potential impact on programs and site visits. Find information here.

Nuclear Medicine Technology Certification Board (NMTCB)

• Update on Testing Resumption for NMTCB Examinations (April 13)
• Information from NMTCB for certified technologists, NMT educators, students, and exam applicants.

Resources for Residents

• Impact of COVID-19 on Radiology Residents and Resident Education (RSNA On-Demand Webinar, May 20) 
• ACGME Information for Residents and Fellows

Resources for Students

• Update on NMT Training from ARRT and NMTCB (April 2020)

Government Resources

World Health Organization (WHO)

• Coronavirus Disease Technical Guidance
• Advice on the use of masks
• Considerations for stopping laboratory activities
• Considerations for stopping clinical research activities

Centers for Disease Control and Prevention (CDC)

• Decontamination and Reuse of Filtering Facepiece Respirators 
• Healthcare Infection Prevention and Control FAQs (PPE guidance for healthcare workers — April 1)
• Healthcare Supply of Personal Protective Equipment
• Information for Healthcare Professionals
• Interim Guidance for Healthcare Facilities: Preparing for Community Transmission of COVID-19 in the United States (Feb. 29)
• Interim U.S. Guidance for Risk Assessment and Public Health Management of Healthcare Personnel with Potential Exposure in a Healthcare Setting to Patients with Coronavirus Disease (COVID-19)
• Interim Infection Prevention Guidelines (March 19)
• Prepare to Care for COVID-19: Get Your Practice Ready
• Resources for Clinics and Healthcare Facilities
• Sequence for Putting On Personal Protective Equipment

Centers for Medicare and Medicaid Services (CMS)

• Coronavirus Waivers & Flexibilities
• Recommendations Re-opening Facilities to Provide Non-emergent Non-COVID-19 Healthcare: Phase I (April 19)
• New and Expanded Flexibilities for Rural Health Clinics and Federally Qualified Health Centers... (April 17)
• CMS relief for providers participating in quality reporting programs
• CMS Releases Recommendations on Non-Essential Medical Procedures During COVID-19 Response (March 18)
• CMS Coronavirus Response
• Medicare Telehealth Frequently Asked Questions (FAQs) (March 17)

Department of Defense

• COVID-19 FAQs for Grant Applicants and Recipients (Version 2, March 25)

Department of Health and Human Services (HHS) Office for Civil Rights (OCR)

• Recent HHS Updates During the COVID-19 Pandemic (May 19) 
• CARES Act Provider Relief Fund
• Notification of Enforcement Discretion for Telehealth

Food and Drug Administration (FDA)

• FDA Coronavirus Disease 2019
• FDA Guidance on Clinical Trials
• FDA: Guidance to Increase Availability of Ventilators

National Academy of Medicine (NAM)

• Duty to Plan: Health Care, Crisis Standards of Care, and Novel Coronavirus SARS-CoV-2

National Cancer Institute (NCI)

• Coronavirus: Guidance for Cancer Researchers

National Institutes of Health (NIH)

• NIH Coronavirus Disease 2019 Center
• NIH Guidance on Grants, Operations During COVID-19 Response
• Information for NIH Applicants and Recipients of NIH Funding

National Science Foundation

• Impact on Existing Deadline Dates (NSF) 
• FAQs About COVID-19 for NSF Proposers and Awardees

Nuclear Regulatory Commission

• NRC Townhall Meeting: COVID-19 Regulatory Relief for Medical and Other Materials Licensees (November 17—meeting summary and slides)
• Regulatory Relief Pathways for NRC Medical Licensees During the COVID-19 Public Health Emergency (April 22)
• Medical Licensee Temporary Exemptions During the Emergency Caused by the COVID-19 Pandemic (April 8)
• U.S. Nuclear Regulatory Commission Methods for Providing Regulatory Relief During the Coronavirus Disease 2019 Public Health Emergency (April 7)

Other Resources

American College of Physicians

• Telehealth Coding and Billing During COVID-19
• Coronavirus Disease 2019 (COVID-19): Information for Internists

American College of Radiology

• ACR Statement on Safe Resumption of Routine Radiology Care During the COVID-19 Pandemic 

American Medical Association

• A Physician’s Guide to COVID-19
• COVID-19 Resource Center for Physicians
• Quick Guide to Telemedicine

Association of American Medical Colleges

• AAMC Guidance on Medical Students' Clinical Participation

COVID-19 Data Websites

• COVID-19 Open Research Dataset (CORD-19)—Allen Institute of Artificial Intelligence has partnered with research groups on this free resource of more than 47,000 scholarly articles about COVID-19 for use by the global research community.
• Live global data about COVID-19
• COVID-19 in the US and Canada (includes state and county-level data)

DOTmed

• DOTmed has created a COVID-19 equipment redeployment program to help hospitals support one another as they combat coronavirus.

ECRI

• COVID-19 and Medical Devices: Safe Respirator Usage When Supplies Are Short

Elsevier Novel Coronavirus Information Center

• Free health and medical research on COVID-19

European Association of Nuclear Medicine (EANM)

• COVID-19 Information Centre

International Atomic Energy Agency (IAEA)

• COVID-19 Information

MIM Software

• During the pandemic, MIM Software is making free licenses available to its users so they can work from home. Request a license.

North American Neuroendocrine Tumor Society (NANETS)

• COVID-19 Resource Page

Radiation Research Society

• Commentary: Low-Dose Radiation Therapy (LDRT) for COVID-19: Benefits or Risks? (October 12) 

Radiological Society of North America (RSNA)

• Surge Preparedness (May 6) 
• RSNA COVID-19 Task Force: Post-COVID Surge Radiology Preparedness (May 6) 
• COVID-19 Resources

Sterilizing Masks for Reuse

These articles may be helpful if you need to stretch your supply of respirators. See also ECRI video above and CDC article under Government Resources tab. Please note: Several of these articles are preprints and have not yet been peer reviewed. Accordingly, they are provided for informational purposes only and should not be used to guide clinical practice.

• Hydrogen Peroxide Vapor sterilization of N95 respirators for reuse
  Patrick A. Kenney, Benjamin K. Chan, Kaitlyn Kortright, Margaret Cintron, Nancy Havill, Mark Russi, Jaqueline Epright, Lorraine Lee, Thomas J. Balcezak, Richard A. Martinello

• Decontamination and Reuse of N95 Respirators with Hydrogen Peroxide Vapor to Address Worldwide Personal Protective Equipment Shortages During the SARS-CoV- (COVID-9) Pandemic
  Antony Schwartz, Matthew Stiegell, Nicole Greeson, Andrea Vogel, Wayne Thomann, Monte Brown, Gregory D. Sempowski, Thomas Scott Alderman, James Patrick Condreay, James Burch, Cameron Wolfe, Becky Smith, Sarah Lewis

• N95 Filtering Facepiece Respirator Ultraviolet Germicidal Irradiation (UVGI) Process for Decontamination and Reuse
  John J Lowe, Katie D Paladino, Jerald D Farke, Kathleen Boulter, Kelly Cawcutt, Mark Emodi, Shawn Gibbs, Richard Hankins, Lauren Hinkle, Terry Micheels, Shelly Schwedhelm, Angela Vasa, Michael Wadman, Suzanne Watson, and Mark E Rupp

• Evaluation of Five Decontamination Methods for Filtering Facepiece Respirators
  Dennis J. Viscusi, Michael S. Bergman, Benjamin C. Eimer, Ronald E. Shaffer

• What are good ways to address the shortage of face masks by anesthesiologists?
  Amy Price, DPhil (Oxon) and Larry Chu, MD, on behalf of the Stanford AIM Lab and Learnly COVID-19 Evidence Service

• Stability of SARS-CoV-2 in different environmental conditions
  Alex Chin, Julie Chu, Mahen Perera, Kenrie Hui, Hui-Ling Yen, Michael Chan, Malik Peiris, Leo Poon

• UV Sterilization of Personal Protective Equipment with Idle Laboratory Biosafety Cabinets During the COVID-19 Pandemic
  Theory Division, Cleveland Clinic Lerner Research Institute, Kyle J Card, Dena Crozier, Andrew Dhawan, Mina Dinh, Emily Dolson, Nathan Farrokhian, Vishhvaan Gopalakrishnan, Emily Ho, Eshan S King, Nikhil Krishnan, Gleb Kuzmin, Jeff Maltas, Julia Pelesko, Jessica A Scarborough, Jacob G Scott, Geoff Sedor, Davis T Weaver